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Applications Of Choline-Based Ionic Liquids In Drug Delivery

Di: Stella

Abstract Cholinium-based ionic liquids are compounds increasingly studied in pharmaceutics and biomedicine to enhance bioavailability in drug delivery systems and as bioactive ingredients in pharmaceutical formulations. Abstract Ionic liquids (ILs) and deep eutectic solvents have shown great promise in drug delivery applications. Choline-based ILs, in particular choline and geranic acid (CAGE), have been

Transdermal delivery of drugs is more challenging for drugs that are insoluble or sparingly soluble in water and most organic solvents. To overcome this problem, ionic liquid Oral insulin formulation is a recent development in drug delivery systems. Biocompatible choline-based ionic liquids (ILs) show promising antibacterial activity and are useful for oral and

(PDF) Choline-Based Ionic Liquids as Media for the Growth of ...

This review summarize the ILs and IL-based gel structures with their advanced drug delivery applications. The first part of review focuses on the role of ILs in drug formulation The typical and promising properties of ionic liquids facilitate wide applications of ionic liquid-based liquid formulations in the field of biomedicine, to improve the solubility and Choline and geranic acid (CAGE)-based ionic liquids have been recently developed for applications in drug delivery. Understanding the microscopic structures of CAGE in the

Ionic liquid-based gels for biomedical applications

Beyond their traditional use as green solvents, new applications have become available for ionic liquids (ILs) in drug delivery. Their flexible tunability enables task-specific nature ILs show Ionic liquids (ILs) show promises as chemical penetration enhancers (CPEs) for transdermal delivery of macromolecular drugs. However, their high viscosity and strong drug-IL

Abstract Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids

Choline Geranate Dec 2024 Ionic liquids, organic salts in a liquid state below 100 °C, have traditionally been associated with industrial applications. Recent research has introduced a

  • Ionic Liquids-Based Drug Delivery: a Perspective
  • Ionic liquid-based gels for biomedical applications
  • Ionic liquids: Emerging chemical permeation enhancers
  • Ionic liquids: a state of the art for biomedical applications

As both publications and patent applications grow rapidly, a booming amount of research on IL-based drug delivery is expected in the coming years. Nonetheless, the

Topical administration of CyA circumvents systemic side effects; however, the poor water solubility and large molecular weight of CyA pose challenges for dermal delivery. In

Ionic Liquids in Pharmaceutical and Biomedical Applications: A

Boosted by the simplicity of their synthesis and low toxicity, cholinium and amino acid-based ionic liquids have attracted the attention of researchers in many different fields ranging from

The structure of choline-amino acid ionic liquids, atoxic task-specific solvents composed of materials originated from renewable feedstocks, is reviewed in this letter. The varied and strong interactions that these liquids are capable of Ionic liquids, consisting of a bulky, asymmetric cation and geranic acid CAGE and an anion, have attracted significant interest in a broad range of applications, including catalysis and energy Ionic liquids based on choline carboxylic acids have shown impressive advances in drug-delivery applications 4, including in the transdermal, buccal and oral delivery of insulin,

Almeida TS, Júlio A, Saraiva N et al (2017b) Choline-versus imidazole-based ionic liquids as functional ingredients in topical delivery systems: cytotoxicity, solubility, and skin permeation

Abstract Ionic liquids (ILs) and deep eutectic solvents have shown great promise in drug delivery applications. Choline-based ILs, in particular choline and geranic acid (CAGE),

Applications of Bio-IL in drug formulation and delivery systems. 2. Biocompatible Ionic Liquids (Bio-ILs) in Drug Formulation ILs are widely applied to pharmaceutics and medicines, which

Surface-active ionic liquids (SAILs) are the category of ionic liquids specifically with long hydrophobic alkyl chains. Besides as an eco-friendly alternative to organic solvent, an exciting and promising a Abstract Low solubility restricted transdermal penetration of drugs. We aimed to develop a novel ionic liquid-iontophoresis (IL-IS) technology and assess their efficacy and

Cholinium amino acid-based ionic liquids

Abstract: The development of effective forms to incorporate poorly soluble drugs into delivery systems remains a problem. Thus, it is important to find alternatives such as finding excipients The physicochemical properties of ionic liquids (ILs) in transdermal drug delivery (TDD) directly affect that are insoluble or drug permeation efficiency. Understanding the relationship between the molecular structure of ILs and Ionic liquids, organic salts in a liquid state below 100 °C, have traditionally been associated with industrial applications. Recent research has introduced a new generation of ionic liquids,

Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids Ionic liquids (ILs) represent an exciting and promising solution for advancing drug delivery platforms. Their unique properties, including broad chemical diversity, adaptable

Ionic liquids (ILs) usually refer to kinds of salts with melting point below 100 °C and are composed of definite anions and cations. In recent years, in addition to the field of material engineering, Transdermal administration is of high interest for drug delivery due to its non-invasiveness and easy dosing. However, this route of drug delivery faces the challenges of low

Ionic liquids (ILs) consist of poorly coordinated ions for contributing important physical properties in the liquid form at room temperature. Due to volatile nature, ILs show less Abstract Ionic liquids (ILs) have been proven to be an effective technology for enhancing drug transdermal absorption. However, due to the unique structural components of ILs, the design Abstract A number of studies are on the way to advancing the field of biomedical sciences using ionic liquids (ILs) and deep eutectic solvents (DESs) in view of their unique properties and

Paula Berton and Julia L. Shamshina Abstract Transdermal administration is of high interest for drug delivery due to its non-invasiveness and easy dosing. However, this route of drug delivery

Caribbean Journal of Science and Technology, 2019 In this review the author summarized various applications of Ionic liquids such as solvents, electrolytes, catalysis, solar cells, fuel cells,

The unique properties of ionic liquids (ILs), such as structural tunability, good solubility, chemical/thermal stability, favorable biocompatibility, and simplicity of preparation, Ionic liquids (ILs) have emerged as a cutting-edge frontier in the realm of science and technology, offering a unique blend of tunable physicochemical and biological features with