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General

Chewing Gum As A Drug Delivery System

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Medicated chewing gums (MCGs) represent a unique platform for drug delivery. They have been defined as solid single-dose preparations, which may contain more than one active pharmaceutical ingredient (API) with base consisting primarily of gum that has to be chewed for a certain period of time. They mainly contain a tasteless masticatory gum base as Medicated chewing gum is an innovative approach which is used as a drug delivery vehicle for pharmaceutical and nutraceutical ingredients. Medicated chewing gum is a solid, single dosage form ABSTRACT People of all cultures chew gum, and a variety of gums and gum-like substances have been enjoyed for thousands of years. The introduction and subsequent success of Nicotine chewing gum in the 1980’s paved the way for a more general acceptance of chewing gum as a drug delivery system. Improved technology and extended knowl-edge, together with the

(PDF) Medicated Chewing Gum: A Novel Drug Delivery System - DOKUMEN.TIPS

Chewing gums are mobile drug delivery systems. Unlike chewable tablets medicated gums are not supposed to be swallowed and may be removed from the site of application without resort to invasive means and medicated chewing gum MCG is solid, single dose preparation. As for as patient convenience is concerned it is discrete and easy administration without water promotes Abstract While formulating drug delivery system intended to act locally in oral cavity, chewing gum placed on oral mucosa, which is highly vascular, can be considered as a potential substrate carrier.

Medicated chewing gum: An unconventional drug delivery system

Nystatin is an antifungal drug with a poor solubility in water and saliva. Consequently, only a small amount of the drug was released from nystatin chewing gum during testing on a mastication devic Results. Gum-drug interactions, mechanisms Gum driven drugs could of release, and formulations of the drugs might all play a role in this versatile delivery method. Accordingly, chewing gum-based carriers may be presented as a plausible candidate for drug delivery in oral diseases. Conclusion.

Download Citation | Miconazole and Miconazolenitrate Chewing Gum as Drug Delivery Systems – A Practical Application of Solid Dispersion Technique | Abstract Miconazole and miconazolenitrate are Mobile drug delivery system is another term for medicated chewing gum. As proven by nicotine gum, the correct delivery system can have a substantial impact on success by giving product differentiation in the market.

Results. Gum-drug interactions, mechanisms of release, and formulations of the drugs might all play a role in this versatile delivery method. Accordingly, chewing gum-based carriers may be presented as a plausible candidate for drug delivery in oral diseases. Conclusion. Abstract: One portable method of medicine delivery is chewing gum. It may be used to provide medications orally, either systemically or locally.In recent years, significant progress has been made in research and technology related to the oral medication administration route. Medicated chewing gum has gained international attention throughout the year due to its ability to Gum-driven drugs could be introduced as promising candidates for treating oral diseases due to their ability to deliver the proper local dosages of active ingredients, short contact time, biocompatibility, and biodegradable chemical structures.

  • What Are Medicated Chewing Gums?
  • FORMULATION DEVELOPMENT OF CHEWING GUM AS A NOVEL DRUG DELIVERY
  • Medicated chewing gum, a novel drug delivery system

Chewing gums are mobile drug delivery systems. It is a potentially useful means of administering drugs either locally or systemically via the oral cavity. The medicated chewing gum has through the Chewing gums are mobile drug delivery systems. It is a potentially useful means of administering drugs either locally or systemically via, the oral cavity. The medicated chewing gum has through Readers will gain knowledge about the rationale and prominent formulation and performance evaluation strategies behind chewing gum as a drug delivery system.

Accordingly, chewing gum-based carriers may be presented as a plausible candidate for drug delivery in oral diseases. Chewing gum known as gum base (insoluble gum base resin) contains elastomers, emulsifiers, fillers, waxes, antioxidants, softners, sweeteners, food colorings, flavoring agents, and in case of medical chewing gum, active substances. It offers various advantages over conventional drug delivery systems.

What Are Medicated Chewing Gums?

Chewing gum is recognized as a possible drug delivery method, but there currently aren’t any reliable ways of testing how much of a particular compound they can release during use.

While formulating drug delivery system intended to act locally in the oral cavity, chewing gum placed on oral mucosa, which is highly vascular, can be considered as a potential substrate carrier

With a mounting demand for alternative drug delivery systems and extensive knowledge of the product, a novel and consumer-friendly dosage form can be developed in the form of a medicated chewing gum [3, 4]. The right delivery system can significantly impact success by providing product distinctiveness in the market, as evidenced by nicotine gums. Chewing gum is represent a unique platform an excellent drug delivery system for self medication, as it is convenient and can be administered discretely without water. It offers several advantages compared to chewable What the reader will gain: Readers will gain knowledge about the rationale and prominent formulation and performance evaluation strategies behind chewing gum as a drug delivery system.

New formulations and technologies have been developed through oral drug delivery systems‘ researches. Such researches display significance of oral route amongst patients. We’ve reviewed all the is convenient Abstract The release of the antifungal drug miconazole from chewing gum was evaluated both in vitro and in vivo. It was proved that the addition of lecithin and the application of a miconazole

The objective of the present study was to formulate Metronidazole benzoate as Medicated Chewing Gum to prove acceptable of patients and enhance its antibiotics as a drug delivery system.

(PDF) Medicated chewing gum: as a new generation drug carrier/dosage form

It wasn’t until 1978 that nicotine chewing gum, which was acknowledged as a powerful drug delivery mechanism, became commercially accessible.

Medicated chewing gum, a novel drug delivery system

New formulations and technologies have been developed through oral drug delivery systems’ researches. Such researches display significance of oral route amongst patients. We’ve reviewed all the features associated with medicated chewing gum as a modern drug delivery by introducing the history, advantages and disadvantages, methods of manufacturing, composition Chewing gum known as gum base (insoluble gum base resin) contains elastomers, emulsifiers, fillers, waxes, antioxidants, softners, sweeteners, food drug delivery in colorings, flavoring agents, and in case of medical chewing gum, active substances. It offers various advantages over conventional drug delivery systems. ABSTRACT Chewing gums are mobile drug delivery systems. It is a potentially useful means of administering drugs either locally or systemically via the oral cavity. The medicated chewing gum has through the years gained increasing acceptance as a drug delivery system. Several ingredients are now incorporated in medicated chewing gum, e.g. Fluoride for

Medicated chewing gum is one of the most attractive forms of the drug delivery system because of its fast mechanism of action.

Chewing gum can be used as drug delivery for many active components. With the inclusion of medical chewing gum in may be presented as the European Pharmacopoeia in 1998, have further contributed to the acceptance of this method of drug delivery.

Abstract Medicated chewing gum (MCG) consider as a mobile system for drug delivery. It consists of a gum base, active ingredient, and other substances such as sweeteners oral drug and plasticizers. M edicated chewing gums are the up-to-the-minute novel drug delivery system gaining much acceptance as an oral drug delivery system.

Abstract The release of the antifungal drug miconazole from chewing gum was evaluated both in vitro and in vivo. It was proved that the addition of lecithin and the application of a miconazole with the in vivo results polyethyleneglycol 6000 solid dispersion increased the release of miconazole from chewing gum. The in vitro results correlated well with the in vivo results. 6 healthy volunteers

Abstract The purpose of this work is to develop a new formulation of nystatin using chewing gum as a drug delivery system to optimize the drug release rate in order to improve the desired efficacy in the site of action for treating patients with oral candidiasis. Chewing gum can be used as a mobile medication delivery device for both local and systemic drug administration via the oral route. What the reader will gain: Readers will gain knowledge about the rationale and prominent formulation and performance evaluation strategies behind chewing gum as a drug delivery system. Take home message: The availability of directly compressible co-processed gum material enables rapid, safe and low-cost development of MCG as a drug

Medicated chewing gum has a history for about a century. Now-a-days it is considered to be a potential and convenient modified release drug delivery system which can be used in pain relief medication, smoking cessation, travel illness, freshening of breath, prevention of dental caries, alleviation of xerostomia, vitamin or mineral supplementation etc. Medicated chewing gums are