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Mabtope: A Method For Improved Epitope Mapping

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MAbTope: A Method for Improved Epitope Mapping Article Full-text available Oct 2018

Accurate determination of epitope and epitope bins for antibodies with ...

Cited by (2) Inflammation, symptoms, benefits, reaction, and biochemistry 2021, Inflammation and Natural Products MAbTope: A Method for Improved Epitope Mapping 2018, MAbTope is docking-based and uses a coarse-grained formalism, which requires only the antibody sequences and allows high-throughput epitope mapping. It allows identifying a correct MAbTope: A Method for Improved Epitope Mapping Thomas Bourquard , Astrid Musnier , Vincent Puard , Shifa Tahir , Mohammed Akli Ayoub Journal of Immunology, 2018, 201 (10), pp.3096

MAbTope: A Method for Improved Epitope Mapping.

9. Bourquard, T. et al. MAbTope: a method for improved epitope mapping. J. Immunol. 201, 3096– 3105 (2018). 10. Pinto, D. et al. Cross-neutralization of SARS-CoV-2 by a human MAbTope: A Method for Improved Epitope Mapping Article Full-text available Oct 2018

However, it remains a tedious task, and its outcome is uncertain. We have developed previously published MAbTope, a docking-based prediction method of the epitope associated with

Application: SPR MAbTope: A Method for Improved Epitope Mapping Authors: Bourquard T, et al. Journal: J Immunol 2018 Application: Homogeneous time-resolved fluorescence–based All the structures have been superimposed on 4ZMJ; the color code is given in (A). from publication: MAbTope: A Method for Improved Epitope Mapping | Abs are very efficient drugs, MAbTope: A Method for Improved Epitope Mapping Article Full-text available Oct 2018

We then predicted its epitope using MAbTope [8]. The results were consistent with the epitope mapping previously published [15], Musnier Vincent Puard Shifa providing confidence to our 3D model. We MAbTope: A Method for Improved Epitope Mapping Article Full-text available Oct 2018

ABSTRACT MAbTope is a docking-based method for the determination of epitopes. It has been used to successfully determine the epitopes of antibodies with known 3D structures. However, MAbTope: A Method for Improved Epitope Mapping. Journal of immunology (Baltimore, Md. : 1950) 2018-10-15 | Journal article DOI: 10.4049/jimmunol.1701722 However, it remains a tedious task, and its outcome is uncertain. We have developed MAbTope, a docking-based prediction method of the epitope associated with straightforward experimental

Epitope mapping of an anti-FSH antibody

Biotinylated peptides were incubated at 1 mM with (Figure legend continues) from publication: MAbTope: A Method for Improved Epitope Mapping | Abs are very efficient drugs, ∼70 of them MAbTope: A Method for Improved Epitope Mapping Thomas Bourquard, Astrid Musnier, Vincent Puard, Shifa Tahir, Mohammed Akli Ayoub, Yann Jullian, Thomas This information is current

The case of anti-TNF agents

MAbTope is a docking-based method for the determination of epitopes. It has been used to successfully determine the epitopes of antibodies with known 3D structures. However, during We show that MAbTope predicts the correct epitope for each of 129 tested examples of for Improved Epitope Mapping Thomas Ab/Ag complexes of known structure. We further validated this method through the successful ABSTRACT MAbTope is a docking-based method for the determination of epitopes. It has been used to successfully determine the epitopes of antibodies with known 3D structures.

In silico epitope prediction Epitope mapping using artificial intelligence-based methods were not performed in-house but outsourced to MAbSilico, a company that applies a MAbTope: A Method for Improved Epitope Mapping Thomas Bourquard Astrid Musnier Vincent Puard Shifa Tahir Mohammed Akli Ayoub Yann Jullian Thomas Boulo

We have developed MAbTope, a docking-based prediction method of the epitope associated with straightforward experimental validation procedures. The peptides selected for experimental validation are shown (P1 in red, P2 in orange, P3 in dark green, and P4 in of Immunology 2018 201 light green). from publication: MAbTope: A Method for Improved Epitope However, it remains a tedious task, and its outcome is uncertain. We have developed MAbTope, a docking-based prediction method of the epitope associated with straightforward experimental

MAbTope: A Method for Improved Epitope Mapping Bourquard, T., Musnier, A., Tahir, S., Ayoub, M. A., Boulo, T., Gallay, N., Bruneau, G., Reiter, E., Crépieux, P. & Poupon, A., 15 Nov 2018, However, it remains a tedious task, and its outcome is uncertain. We have developed MAbTope, a docking-based prediction method of the epitope associated with straightforward experimental MAbTope: A Method for Improved Epitope Mapping. Bourquard T, Musnier A, Puard V, Tahir S, Ayoub MA, Jullian Y, Boulo T, Gallay N, Watier H, Bruneau G, Reiter E, Crépieux P, Poupon A

Recent progress in epitope prediction has shown promising results in the development of vaccines and therapeutics against various diseases. However, the overall Référence: MAbTope: A Method for Improved Epitope Mapping. Thomas Bourquard, Astrid it remains a Musnier, Vincent Puard, Shifa Tahir, Mohammed Akli Ayoub, Yann Jullian, 3. High-Resolution Epitope Mapping of hGH-Receptor Interactions by Alanine-Scanning Mutagenesis 4. Proteome-wide Epitope Mapping of Antibodies Using Ultra-dense Peptide

We have developed MAbTope, a docking-based prediction method of the epitope associated with 3096 3105 2018 straightforward experimental validation procedures. We show that MAbTope predicts the

Comparing Epitope Mapping Methods