Memory Circuits: Ca2 | A hypothalamic novelty signal modulates hippocampal memory
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The classical corticohippocampal glutamatergic circuits. The classical corticohippocampal circuit comprises of glutamatergic input from the superficial entorhinal cortex (EC) layers (LII and LIII) Villegas and Siegelbaum report that the dorsal CA2 region of the hippocampus acts to selectively increase aggression toward novel compared with familiar individuals. Finally, we will discuss the impact of an altered MS signaling on social memory in animal models and patients affected by neurodevelopmental and neurodegenerative disorders, including

A unique role for the CA2 region in social memory The hippocampal CA2 region is a small but critical hub for social recognition—the ability to remember and distinguish
A hypothalamic novelty signal modulates hippocampal memory
Sci-Hub | Memory circuits: CA2. Current Opinion in Neurobiology, 52, 54–59 | 10.1016/j.conb.2018.04.015 to open science ↓ save
The hippocampal dorsal CA2 enables the recognition of novel conspecifics. Kassraian et al. show that it is also required for discriminating safety- versus threat-associated In addition, experimental links between synaptic plasticity of CA3 circuits and memory are starting to emerge.
6 Basic Memory Circuits In this chapter, we take a look at the memory circuits used in programs in the US and in Europe. There are differences. The Allen-Bradley programming language Pharmacogenetic inhibition of the MS to dorsal CA2 circuit impaired social recognition memory (Wu et al., 2021). The afferent and efferent pathways of the ventral
A possible mechanism for the formation of representations of object–place associations in hippocampal neurons based on plastic rearrangements of the efficiency of The formation remains to and recall of episodic memory requires precise information processing by the entorhinal-hippocampal network. For several decades, the trisynaptic circuit entorhinal cortex
The formation and maintenance of episodic memories are important for our daily life. Accumulating evidence from extensive studies with pharmacological, electrophysiological, As CA2 activity is required for both social memory acquired during non-aggressive social exploration and for social aggression, downstream circuits must differentiate when CA2 output
The hippocampus is a central region in the coding of spatial, temporal and episodic memory. Recent discoveries have revealed surprising and complex roles of the small area CA2 in Summary: During sleep, the brain resets memory by silencing specific neurons in the hippocampus, allowing for continuous learning without overloading. This process, crucial Dear Editor, ı ̄Social recognition memory is essential for proper con-specific interactions and its impairments are closely associated with many brain disorders, including autism, schizophrenia,
The Corticohippocampal Circuit, Synaptic Plasticity, and Memory
Several neural circuits associated with social memory have been identified in multiple brain regions, including the hippocampal cornu ammonis subregions 1 2 and 2 3,4 Adaptations of the hippocampus that are likely to reflect the demands of memory processing are immediately apparent in its gross histology: the dense hippocampal cell layers
The hippocampus is critical for encoding declarative memory, our repository of knowledge of who, what, where and when. Mnemonic information is processed in the

Download scientific diagram | EC-HPC neural circuits for episodic memory EC2 contains two populations of excitatory neurons, Reelin + stellate cells and Wfs1 + pyramidal cells. Reelin+ cells
A unique role for the CA2 region in social memory The hippocampal CA2 region is a small but critical hub for social recognition — the ability to remember and distinguish individuals. Mankin et al. show that the firing patterns of hippocampal CA2 neurons do not persistently code for space or differences in context, but rather change over time. This is
Updating hippocampal representations: CA2 joins the circuit
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- Memory circuits: CA2,Current Opinion in Neurobiology
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- The Corticohippocampal Circuit, Synaptic Plasticity, and Memory
Hippocampal area CA2 plays a critical role in social recognition memory and has unique cellular and molecular properties that distinguish it from areas CA1 and CA3.
Hippocampal region CA2 has received increased attention due to its importance in social EC layers LII recognition memory. While its specific function remains to be identified, there are
These findings help us explore potential targeting brain areas or circuits of social communication disorder. Keywords: social recognition memory, dorsal CA2, ventral CA1, social isolation, This brief review first summarizes the brain regions and neural circuits related to social recognition memory, mainly dorsal CA2 and ventral CA1, and their upstream and downstream circuits,
Social memory consists of both familiarity detection and recollection of past social episodes. Whether and how the hippocampus fulfills these roles is unclear. Boyle, Posani, et
For several decades, the trisynaptic circuit entorhinal cortex layer II (ECII)→dentate gyrus→CA3→CA1 and the monosynaptic circuit ECIII→CA1 have been considered the primary
Article „Memory circuits: CA2“ Detailed information of the J-GLOBAL is an information service managed by the Japan Science and Technology Agency (hereinafter referred to as „JST“). It The formation and recall of episodic memory requires precise information processing by the entorhinal-hippocampal network. For several decades, the trisynaptic circuit
The hippocampal CA2 region plays a key role in social memory. The encoding of such memory involves afferent activity from the hypothalamic supramammillary nucleus (SuM) Entorhinal cortex transfers multimodal information to hippocampus CA1 neurons via indirect and direct pathways. The authors show that excitatory projections from lateral
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