Rare Ovarian Tumors | Rare malignant ovarian tumors: a review

Di: Stella

There are several types of ovarian cancers. These types are broken out by the types of cells they originated from, how they appear to researchers when being studied, and how they behave. Ovarian cancer starts from three common cell types: Epithelial cells – epithelial cells cover the outer lining of the ovaries. Most ovarian cancers are epithelial cell tumors. Germ cells – germ It is important to be aware of these rare entities in the pathological diagnosis of ovarian tumors. Intraoperative frozen examination should be performed because rare benign conditions that mimic malignancy may not require radical surgery. The rarity of Rare gynaecological cancers encompasses a broad group of different tumour types that can be divided conveniently into three groups: Gestational trophoblastic disease (GTD), Rare ovarian tumours, All other rare gynaecological cancers arising in the uterus, cervix, vagina and vulva.

Rare type of epithelial ovarian cancer that is more likely to be diagnosed while it is still confined to the ovaries. Prevalence: Rare, with a tendency to be large. Characteristics: Diagnosis can be challenging due to similarities with metastatic tumors from other organs. Summary Objective: The present study aims to review cases of extremely rare primary ovarian tumors and thus, to evaluate the distribution of rare primary ovarian pathologies. Various aspects of the presentation, diagnosis, and treatment of these tumors are discussed. Materi-als and Methods: A retrospective review of women with final pathology of rare primary ovarian tumors, Androgen-secreting tumors are rare ovarian or adrenal neoplasms associated with virilization symptoms such as hirsutism, deepening of the voice, and menstrual irregularities. These tumors present a diagnostic challenge due to overlapping features with conditions like polycystic ovary syndrome (PCOS) and congenital adrenal hyperplasia

Rare types of ovarian cancer

Ovarian Cancer Tumor Types

For these tumours alternative study designs, robust collection of data through national registries and audits could lead to improvements in the treatment of rare tumours. In addition, concentring the care of patients with rare tumours into a limited number of centres will help to build expertise, facilitate trials and improve outcomes. Granulosa cell tumors of the ovary have an indolent behavior and a good prognosis, but a high incidence of local recurrence after surgery. The best treatment in the recurrent setting is unclear and randomized clinical trials on the management in the recurrent setting are lacking. The role of radiotherapy is controversial in adjuvant settings and unknown in case of relapse after surgery. The description of rare malignant ovarian tumours and the most suitable treatments. Alternative therapies different from intravenous chemotherapy are

Abstract Purpose of review: In spite of their rarity when considered individually, the sum of all rare ovarian tumours (ROT) represent almost half of all ovarian malignancies. As such, their appropriate inclusion within dedicated clinical trials is essential for enhanced management. Given the molecular heterogeneity and the histopathological rarity of these ovarian cancers, the importance of designing adequately powered trials or finding statistically innovative ways to approach the treatment of these rare tumors has been emphasized.

A Sertoli-Leydig cell tumor (SLCT) is a rare ovarian tumor that often excessively secretes testosterone and its precursor, leading to virilization in females. We present a case of a female patient with persistent, severe hyperandrogenism. Our Germline genetic analysis and identification of somatic mutations in tumor tissue provide data for the use of targeted agents and immunotherapy. High grade serous carcinomas comprise 70% of diagnoses, but rare ovarian cancers affect women characterized by a wide spectrum of ages and risk factors.

What Are the Types of Ovarian Cancer?
Detailed overview on rare malignant ovarian tumors
Mucinous Cancer of the Ovary: Overview and Current Status

Ovarian cancer in children and adolescents is rare, presenting unique diagnostic and management challenges distinct from adult cases. This paper provides a comprehensive overview of this disease, focusing on the importance of a multidisciplinary approach to care. We discuss the common presentation of ovarian malignant masses in young patients, highlighting Rare ovarian cancers occur frequently. Almost half of ovarian malignancies relate to several different cell tumors and metastatic lesions ‚rare‘ histotypes, according to the World Health Organization. The most common tumors are epithelial tumors, including high grade serous carcinomas, the presumed ‚frequent ovarian cancers‘, together with low grade serous, mucinous, endometrioid, clear cell, Rare ovarian cancers occur frequently. Almost half of ovarian malignancies relate to several different ‘rare’ histotypes, according to the World Health Organization. The most common tumors are

Mucinous ovarian cancer (MOC) is a rare subtype of epithelial ovarian carcinoma (EOC). Whereas all EOC subtypes are addressed in the same way, MOC is a distinct entity. Appreciating the pathological features and genomic profile of MOC may result in

Rare malignant ovarian tumors: a review

Rare TumorS Lab | IDIBELL

Download Citation | On Aug 6, 2022, Aaron Varghese and others published Rare Ovarian Tumors | Find, read and cite all the research you need on ResearchGate Ovarian cancer (ovarian carcinoma) occurs when cells in the ovary become mutated and begin growing out of control. Because there are different types of cells that make up the ovary, there are many subtypes called epithelial ovarian cancer subtypes of ovarian cancer. Most cases of ovarian cancer are subtypes called epithelial ovarian cancer, which is by far the most common. There are also many In this case report, corresponding author Naina Kumar from the All India Institute of Medical Sciences and team describe a rare ovarian tumor in a 70-year-old postmenopausal woman. The tumor was

A diagnosis of a rare ovarian cancer can feel shocking and scary leaving ovarian cancer wondering what their treatment and cancer care plans will look like. Ovarian tumors are relatively common and account review of women for ~6% of female malignancies. This article focuses on the general classification of ovarian tumors. For specific tumor features, please refer to the relevant subarticles. Pathology Subtypes Pr

ESMO Rare Cancers is a peer-reviewed, open-access medical journal dedicated to advancing the understanding and management of rare cancers. Our mission is to serve as a platform for the dissemination of high-quality research, clinical experiences, and multidisciplinary discussions aimed at improving the diagnosis, treatment, and overall outcomes of patients with rare and setting is unclear and randomized Introduction and importance: Ovarian tumors are relatively rare in children and adolescent females, with mixed sex-cord-stromal tumors being a specific subtype that has a low incidence and is associated with DICER1 gene mutations. Case presentation: This case report describes a 14-year-old female patient diagnosed with a mixed sex-cord-stromal tumor associated with a

Thus, immunoexpression of P53, P16INK4A, and Erb-B2 have not been associated with rare ovarian tumors. Moreover, the observation that malignant Brenner had P53 overexpression and diploid DNA status in one of the patients is a significant finding of this retrospective study. ABSTRACT Introduction: Ovarian cancer ranks as the third most common cancer among Indian women, contributing to 3% of all malignancies and 6% of cancer-related deaths. While epithelial tumors dominate the spectrum, rare ovarian tumors pose significant diagnostic and therapeutic challenges due to their atypical presentations and varied

Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via Over the past 10 to 15 years, we have observed convergence of several forces that have stimulated enhanced interest in rare ovarian cancers and have allowed with a us to begin the process of unmasking tumor heterogeneity of these tumors, including refinement of pathologic criteria, hypothesis-generating observational studies highlighting differences in clinical behavior Ovarian cancer actually refers to several different types of cancer– more than 30, in fact. The types of ovarian cancer are grouped by the kind of cell where they start. Your ovaries have three

At the Rare Ovarian Tumors Conference held in Tokyo 2015 prior to the 5th Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup (GCIG), young investigators addressed an update on recent advances in the knowledge and treatment of rare ovarian cancers, including low-grade serous, mucinous, and clear cell carcinomas of the ovary. Types of ovarian cancer Epithelial ovarian cancer is the most common type of ovarian cancer. Rare types of ovarian cancer include germ cell tumours (teratomas and dysgerminomas), stromal tumours (granulosa tumours) and sarcomas. In this chapter, we cover a wide variety of ovarian lesions with a focus on benign, borderline, and malignant Brenner tumors. In addition, we touch on a wide range of other rare ovarian neoplasms that every pathologist should be familiar with. This chapter emphasizes

Ovarian clear cell carcinoma (OCCC) is a rare and distinct histological type of epithelial ovarian carcinoma in terms of its histopathological, clinical and genetic features. Patients with OCCC are younger and diagnosed at earlier stages than those with the most common histological type-high-grade s Abstract Ovarian cancer remains one of disease GTD Rare the most lethal gynecologic malignancies, with epithelial ovarian carcinomas accounting for the majority of cases. However, rare malignant ovarian tumors- including sex cord-stromal tumors, germ cell tumors, and metastatic lesions- present unique diagnostic and therapeutic challenges. Due to their low incidence, these tumors are often

JQDN

General